XL2003 on XP on an old AMD xp2400 chip

I have taken my Personal.xls out of XLStart but it keeps running? Evidently
it is still there but windows cannot see it

The Personal.xls is currently 14mb

Each day I update my Personal program on a Compaq laptop with Vista and
transfer across using a USB drive. The vista machine (2.0gig duocore) is
incredibly unreliable and I do not know from one day to the next whether the
code will run. It is normal for vista to encounter a problem and wipe out
the vba code in the process.
I have been having the problem of the Personal.xls running when it is not in
the XLStart on the Vista laptop for sometime. But now it is showing up on
my XP desktop. The result is that I am currently out of business as the
program is the center of my investment business.
Can I simply remove the XLStart folder and create a new one. Or is there
some way of cleaning the folder. Everything I try seems to make the problem
worse. Any help would be greatly appreciated.
Ta,
Martin Wheeler