I'd like an Excel Workbook to always open to a certain worksheet

Next, it should refresh the calculations upon opening.

It should also refresh the calculations upon activation of the sheet later

While open, it should run a routine everytime a value in a given cell changes

Thus, if they open the workbook, it goes to a particular worksheet,
refreshes calculations, and if a particular cell changes, it should perform a
routine

Is this too much to ask? Thanks in advance..