As a guess you file ahs been bloated with unused cells. Follow the directions
here to clean the file up...

http://www.contextures.com/gluten.html
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HTH...

Jim Thomlinson


"MFS" wrote:

I am using a file contains about 10 sheets, each sheet contain 5,000 cell,
each cell contain a function or a formula.

Whenever I open the file it takes long time, also when I close it.

Is there any way I can use to reduce this time, like removing column and
rows that I do not need, or anything else??

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MFS22