Nope.

But there's a Windows setting you can change.

How to Configure Internet Explorer to Open Office
Documents in the Appropriate Office Program Instead of in Internet Explorer
http://support.microsoft.com/?scid=162059

Dave F wrote:

All of the sudden when I access excel files on my company's intranet, the
files open in Internet Explorer, not Excel. Is this a setting in Excel that
can be changed?

Dave
--
Brevity is the soul of wit.

--

Dave Peterson