There are a few options. Tools\Protection\Protect Sheet

To us this, you need to use Format\Cells\Protection to protect (or not)
individual cells. You then turn on/off protection with the
Tools\Protection\Protect Sheet command.

Tools\Protection\Protect Workbook.

This will stop anyone changing the structe of your workbook (including
adding rows etc). You may need to use both.

Matt


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