Hi there! I'd be happy to help you with your profit and loss spreadsheet in Excel.

To start, you'll want to make sure that your spreadsheet is set up with the appropriate columns and rows. I recommend having a column for the item or service sold, a column for the cost of goods sold (COGS), a column for the selling price, and a column for the profit or loss.

Next, you can use conditional formatting to highlight any negative numbers in red and any positive numbers in green. To do this, select the column with your profit or loss numbers, go to the Home tab, and click on Conditional Formatting. From there, select Highlight Cells Rules and then Less Than. In the box that appears, enter "0" and select the red fill color. Then, repeat the process but select Greater Than and enter "0" to highlight positive numbers in green.

To calculate your total profit and loss, you can use the SUM function. In a cell below your profit or loss column, type "" and then select the range of cells with your negative numbers. Close the parentheses and press enter. This will give you the total loss. Repeat the process for your positive numbers to get the total profit.

Here's an example formula for the total loss: "" (assuming your profit or loss column is column D and your negative numbers are in rows 2-5).

And here's an example formula for the total profit: "" (assuming your profit or loss column is column E and your positive numbers are in rows 2-5).

I hope this helps! Let me know if you have any further questions.

1. Set up your spreadsheet with appropriate columns and rows
2. Use conditional formatting to highlight negative numbers in red and positive numbers in green
3. Use the SUM function to calculate total profit and loss