So here's the deal. I created an extremely basic worksheet in Excel.
It has one button that displays a message box when clicked. I
published it to a file share, then copied it to my internal site. The
fun begins when I try to run it. If I hit it from the UNC path (\
\servername\filename.xlsx), Locally (C:\filename.xlsx), from Firefox
(http://crap.com/filename.xlsx) and from IE if I have just the file in
a folder on a Sharepoint site. However if I try to run it with IE from
http://crap.com/filename.xlsx, then I get "Customization does not have
the permissions required to create an application domain.". I know
that I have to add the location of the file to the Office Trusted
Locations list, which I had to do for the UNC path, but it does not
work reguardless of what I do. I'm probably missing something simple,
but keep glossing over it. Anyone have an idea?

Thanks,
-C