What are the problems here?

The first gets an error on execution: "Unable to set the PrintArea
property of the PageSetup class"
1). ActiveSheet.PageSetup.PrintArea = Range(Cells(LastRow - 24, 1),
Cells(LastRow + 1, 12))

The second just doesn't work (doesn't set the PrintArea to the range in
question).
2. Range(Cells(LastRow - 24, 1), Cells(LastRow + 1, 12)).Select
ActiveSheet.PageSetup.PrintArea =
ActiveCell.CurrentRegion.Address

Can someone provide an answer to both questions?