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Default I want to replace the first character in a column of text

We have a client that has several thousand rows of data in a single column
formatted as this example shows: A12345B. Where the alpha characters are
any of the 26 available. They want to change the leading alpha character
from whatever it is presently to an upper case X while leaving the rest of
the line unaffected.

Any and all help appreciated.


 
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