No. (Yes, ok, with SendKeys, but that is extremely unreliable.) The trick is
to make the boxes NOT appear at all. That's done with

Application.DisplayAlerts = False

But then you'd better make sure your code knows what it does, like close
without saving changes, overwriteexisting file, things like that.

--
HTH. Best wishes Harald
Excel MVP
Followup to newsgroup only please

"Benjamin" skrev i melding
...
If every time I run a macro I get a typical message box,
can I program it to automatically respond to it?

For example, if within my macro I close a file and it asks
me if I want to save the changes, can my macro
automatically respond to the message box saying NO?