No, Excel doesn't have section breaks similar to those in Word.
You could print the first pages, then change the setup and print the
last page.
Or put the last page on a separate worksheet, and set its orientation there.

Pam Coleman wrote:
I have a spreadsheet on legal landscape, is there a way to set my last page
to be portrait?


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Debra Dalgleish
Excel FAQ, Tips & Book List
http://www.contextures.com/tiptech.html