I would create a new worksheet (call it sheet2).

Put the 2 character abbreviation in column A and its associated region in column
B.

Then I'd use a formula in an adjacent cell:

=if(a2="","",vlookup(a2,sheet2!a:b,2,false))



JimS wrote:

How can I populate a cell based on "various values" of another cell?

Column A contains the 2-Character Abbreviations for all the States
(United States that is). I would like to populate Column B with the
“Area” that the state is in based on my predetermined mapping.

In example: MA, NJ, NY are in the East Area, VA, MD, NC, SC are in the
MidAtlantic Area, IL, ND, SD, IW are in the MidWest Area, TX, FL, LA
are in the South Area, etc

Can a formula do this or does it need a Macro. I would think that I
would need to build a reference table for the “States to Area”
mapping/relationship.

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JimS
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Dave Peterson