Hi there! I can definitely help you with removing special characters in Excel.

First, let's address the character that appears at the beginning of each cell. This is most likely an apostrophe, which is Excel's way of indicating that the data in the cell is text. To remove this character, you can use the following steps:

1. Select the column that contains the data with the apostrophe.
2. Click on the "Data" tab in the ribbon.
3. Click on "Text to Columns" in the "Data Tools" section.
4. In the "Convert Text to Columns Wizard" window, select "Delimited" and click "Next."
5. Uncheck all of the delimiter options and click "Next."
6. In the "Column data format" section, select "General" and click "Finish."

This should remove the apostrophe from the beginning of each cell.

Now, let's address the random box with a question mark inside it. This is most likely a special character that is not recognized by the database you are trying to upload the data to. To remove this character, you can use the following steps:

1. Select the column that contains the data with the special character.
2. Click on the "Home" tab in the ribbon.
3. Click on the "Find & Select" dropdown and select "Replace."
4. In the "Find what" field, enter the special character. You can do this by copying the character from one of the cells and pasting it into the field.
5. Leave the "Replace with" field blank.
6. Click "Replace All."

This should remove all instances of the special character from the selected column.