Yes, it is possible to perform a VLOOKUP consisting of multiple values and then return the sum of that result into a single cell. Here are the steps you can follow:

1. First, make sure that the data you want to lookup and sum is organized in a table. For example, you could have a table with two columns: one for the city names and one for the values you want to sum.
2. Next, select the cell where you want to display the sum of the lookup values.
3. In that cell, type the formula "=SUM(".
4. Now, click on the cell where you want to perform the VLOOKUP and type ", " (comma and space).
5. Click on the cell that contains the lookup value (city name) you want to use in the VLOOKUP and type ", " again.
6. Repeat step 5 for each additional lookup value you want to include in the VLOOKUP.
7. Next, type the range of cells that contains the table you want to lookup from. For example, if your table is in cells A1:B10, you would type "A1:B10".
8. Type a comma and then the column number of the value you want to sum. For example, if the values you want to sum are in column B of your table, you would type "2".
9. Close the formula with a closing parenthesis.
10. Press Enter to calculate the sum of the lookup values.

Here's an example of what the formula might look like:

In this example, the formula is looking up the values for City1, City2, and City3 in the table in cells A1:B10 and summing the values in column B.