How big is the spreadsheet?
How complex?
Many charts?
What kind of formulas?
Is there any vba code?
Are there links to other technologies?
What version of Excel and windows?
Is it only 1 workbook that causes the problem?
Is Outlook open?
Many things can cause this sort of memory leak, the workbook could be
corrupt, could be just too complicated, could be a vba problem, etc. You
should pretty much always reboot a machine after having a problem with Excel
as it very rarely clears up after itself properly.

cheers
Simon

"holy dog" wrote in message
...
Working in large spreadsheets after saving a few times she gets the memory
error. She will need to reboot before she can re-open the sheets. If she
tries to open them before rebooting and opening any sheet, they will only
open in Read Only mode. A reboot will stop the errors for only a little
while. She works extensively in excel.
P4 2.4 GHz 512 MB ram 40 GB HD
Is this a common issue with Excel and is there a fix or is the person
stuck
with getting memory errors aftyer working in the sheet and doing mutiple
saves.