Thanks for all you input, Mike and Lars code works but not if my sheet is
protected (even if the cell B1 is unprotected). How do I get around this?

I couldn't get Craigs suggestion to work.

"mike" wrote:

Super easy question..I want cell B1 cleared on workbook open.

What I am trying to do: Macros need to be enabled for my sheet to proper,
our business excel macros are off with notification and we want to keep it
that way for most users. Most people here are excel illiterate and don't even
know what a macro is, so in cell B1 I have in bold red instructions for
enabling macros.

If the macro is enabled, I want those contents cleared, or if macros are
already enabled, for those contents to clear on open.

If what I'm asking won't achieve my desired results, please enlighten me.

Thanks,

Mike