Still working on this code:

Sub CtyMatch()
Dim strOrig, strOutcomes As String
Dim rCell, rTOCtyLst As Range
Dim iOrigCityNo, iEndRow As Integer

strOrig = ActiveSheet.Range("A2")
iOrigCityNo = Left(strOrig, 2)
iEndRow = ActiveSheet.Range.Cells(Rows.Count, "B").End(xlUp).Row
Set rTOCtyLst = Range(.Cells(1, 1), .Cells(1, iEndRow))

But am getting an "invalid or unqualified reference" error on the last
line, .Cells being highlighted. I copied this line from another thread
here so I'm stumped as to why it doesn't recognize ".Cells" here but
does elsewhere in a nearly identical situation.
Any suggestions?
Thanks.