Try the following (untested!)

Dim cell as range
for each cell in intersect(columns(1), activesheet.usedrange)
if not isempty(cell) then
cells(cell.row,3).value = 0
cells(cell.row, 5).value = 0
end if
next

Robert Flanagan
Macro Systems
Delaware, U.S. 302-234-9857
http://www.add-ins.com
Productivity add-ins and downloadable books on VB macros for Excel

"Steve" wrote in message
...
I want to populate specific column values with a zero if
the value in another specified column is not null.

As an example, I would like to place a 0 in columns C & E
of my spreadsheet if the value in column A is null.

I presume that I would have to start by specifying the
range which I would like this macro to work over. If that
is so, is it possible for the range to set itself by using
any row that has data on it (bar row1) ? This way, the
range can vary depending on how many rows of data are in
the spreadsheet at any given time.

Thanks in advance.