Is there a way to start excel in "safe mode" programmatically.

I am creating an excel application instance as mentioned below:-

Excel.Application excelApp = new Excel.Application ();

I do not want to load add-ins and it's my understanding that the "safe mode"
suppresses all add-ins.

Also, I do not want to affect any other instances of the excel application
which may be running add-ins.

Please advise.

Thanks,
Abhishek