Sub DataSave()
Dim Rng As Range
Set Rng = Range("S2:S293")
Sheets("Sheet1").Range("C" & Range("A1")).Resize
(Rng.Cells.Count).Value = Rng.Value
Beep
End Sub

Thanks to your help, this is working nicely.
Trying something new, I am on Sheet2 and I would like to use
Set Rng = Range("S2:S293")
to select cells on Sheet1 and copy to sheet2.