Comparing two data ranges for differences.
 

Is there any easy way to take two ranges of data and compare their contents
for differences.

In particular im working with a rather large list of domains and attempting
to compare two columns to determine what websites are different between the
two. I've tried conditional formating, wont let you use a range as the
target and tried searching for a formula to use without any luck. Any
suggestions would be useful or even if someone could point me in the right
direction.