I thare any way to execute more than one worksheet change per worksheet; say
for cells "A1" and "E1"?

Private Sub Worksheet_Change(ByVal Target As Range)
Dim KeyCells As Range

' The variable KeyCells contains the cells that will
' cause an alert when they are changed.
Set KeyCells = Range("A1") 'another code for cell E1??

If Not Application.Intersect(KeyCells, Range(Target.Address)) _
Is Nothing Then

' Display a message when one of the designated cells has been
' changed.
' Place your code here.

End If
End Sub