Claus, Thanks (!).

After run the macro all the columns F till BZ are hidden :)
But... There are only a few cells in the range 'F3 till BZ last row' with a collored cell. The macro hides them all.

Only the columns without any colored cell in one of the rows of that specific column should be set on hide (hide if at least one of the cells in all the used rows has a fill color).

Can you please have a look on it.
The part with the numbers wordks perfect !

regards, Johan.

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Sub Test()
Dim myRow As Range, rngC As Range, myRng As Range
Dim i As Integer, myCnt As Integer, Counter As Integer
Dim LRow As Long

With ActiveSheet
LRow = .Cells(.Rows.Count, "E").End(xlUp).Row
For Each myRow In .Range("F1:BZ" & LRow).Rows
Counter = 0
For i = .Columns("F").Column To .Columns("BZ").Column
If .Cells(myRow.Row, i).Interior.ColorIndex < xlNone Then
.Cells(myRow.Row, 1) = 1
Exit For
Else
Counter = Counter + 1
End If
Next
If Counter = 73 Then .Cells(myRow.Row, 1) = 0
Next

For i = 1 To LRow
myCnt = Application.CountIf(.Range("E1:E" & LRow), .Cells(i, "E"))
If myCnt 1 Then
Set myRng = .Cells(i, 1).Resize(myCnt)
myRng.Select
If Application.CountIf(myRng, 1) 0 Then
myRng = 1
i = i + myCnt - 1
End If
End If
Next
For Each rngC In .Range("F3:BZ3")
If rngC.Interior.ColorIndex = xlNone Then rngC.EntireColumn.Hidden = True
Next
End With
End Sub